1228879-37-5: A Comprehensive Overview of 1-Benzyl-N,4-Dimethyl-3-Piperidinamide Dihydrochloride

CAS No. 1228879-37-5, known as 1-Benzyl-N,4-Dimethyl-3-Piperidinamide Dihydrochloride, is a specialized chemical compound widely used in pharmaceutical and chemical research. With its unique molecular structure and high purity requirements, this compound plays an important role as an intermediate in advanced synthesis and R&D applications.

This article provides a comprehensive overview of its chemical properties, structure, applications, handling, and research significance.


Chemical Identification

The dihydrochloride form enhances stability and solubility, making it suitable for laboratory and industrial research environments.


Molecular Structure and Properties

1-Benzyl-N,4-Dimethyl-3-Piperidinamide Dihydrochloride features a piperidine ring substituted with benzyl and dimethyl amide groups. This structural configuration is important for:

  • Improved chemical reactivity

  • Enhanced binding characteristics

  • Compatibility with multi-step synthesis pathways

Key Properties:

  • High chemical stability

  • Good solubility in polar solvents

  • Suitable for controlled laboratory synthesis


Applications in Research and Industry

Pharmaceutical Research

This compound is primarily used as a research intermediate in drug discovery and medicinal chemistry. Piperidine derivatives are commonly associated with:

  • CNS-active compounds

  • Analgesic and anesthetic research

  • Neurological and receptor-based studies

Chemical Synthesis

  • Acts as a building block for complex organic molecules

  • Used in structure–activity relationship (SAR) studies

  • Supports the development of novel compounds in R&D pipelines

Academic and Industrial R&D

Research institutions and chemical manufacturers rely on CAS 1228879-37-5 for:

  • Method development

  • Process optimization

  • Advanced compound screening


Handling and Storage

To maintain quality and performance:

  • Store in a cool, dry, and well-ventilated area

  • Keep tightly sealed and protected from moisture

  • Handle using standard laboratory safety practices

  • Use appropriate PPE, including gloves and eye protection

Proper storage ensures long shelf life and consistent research outcomes.


Quality and Compliance

High-quality 1-Benzyl-N,4-Dimethyl-3-Piperidinamide Dihydrochloride is typically supplied with:

  • Certificate of Analysis (COA)

  • Verified purity levels

  • Batch traceability

Ensuring compliance with research and regulatory standards is essential for reliable experimental results.


Conclusion

CAS 1228879-37-5 (1-Benzyl-N,4-Dimethyl-3-Piperidinamide Dihydrochloride) is a valuable compound in modern chemical and pharmaceutical research. Its structural versatility, stability, and compatibility with complex synthesis make it an essential intermediate for scientists and manufacturers alike.

As research continues to evolve, compounds like this remain critical in advancing innovation, drug discovery, and chemical development.