In the world of advanced organic synthesis, 3-Bromo-4-chloropyridine 1-oxide (CAS 99839-30-2) stands out as a versatile intermediate with wide applications across pharmaceuticals, agrochemicals, and fine chemical research. Its unique structure—featuring both bromine and chlorine substituents along with an N-oxide functional group—makes it a valuable building block for complex molecular transformations.
3-Bromo-4-chloropyridine 1-oxide is a heterocyclic organic compound derived from pyridine. The addition of bromine (Br), chlorine (Cl), and the N-oxide group significantly enhances its reactivity and selectivity in various chemical reactions.
CAS Number: 99839-30-2
Chemical Name: 3-Bromo-4-chloropyridine 1-oxide
Molecular Formula: C5H3BrClNO
Category: Pyridine derivative / Organic intermediate
This compound is valued for its reactivity and stability, which makes it ideal for multi-step organic synthesis.
Electrophilic site availability due to halogen substituents
Improved reactivity from the N-oxide group
Suitable for cross-coupling reactions (Suzuki, Buchwald–Hartwig, etc.)
High purity levels available for industrial and research applications
These properties allow chemists to use the molecule as a precursor for numerous downstream compounds.
3-Bromo-4-chloropyridine 1-oxide plays a crucial role in several industries due to its functional versatility.
The compound is widely used in:
Synthesis of API precursors
Development of pyridine-based drug molecules
Construction of heterocyclic frameworks in medicinal chemistry
Its halogenated structure makes it ideal for creating tailored molecular architectures.
It is a preferred intermediate for:
Herbicides
Fungicide formulations
Plant-protection compounds
Its chemical stability and ease of modification make it suitable for designing new crop-care chemicals.
Researchers utilize it for:
Regioselective halogen exchange
Cross-coupling studies
Synthesizing advanced N-oxide derivatives
Developing new catalytic routes
Its combination of Br and Cl improves synthetic flexibility, enabling diverse organic transformations.
The demand for 99839-30-2 is steadily increasing due to its role in:
High-value fine-chemical production
Multi-step API synthesis workflows
Custom synthesis projects in chemical R&D
Manufacturers and research labs value the compound’s:
Consistent quality
Reactivity profile
Compatibility with modern synthesis techniques
As industries continue to develop more complex molecular structures, 3-Bromo-4-chloropyridine 1-oxide remains an essential intermediate in the chemical supply chain.
Although relatively stable, proper handling is important:
Use in a well-ventilated area
Wear appropriate PPE (gloves, goggles, lab coat)
Store away from moisture and incompatible reagents
Always refer to your supplier’s MSDS for detailed safety information.
99839-30-2 (3-Bromo-4-chloropyridine 1-oxide) is a highly valuable compound in today’s chemical industry. Its reactivity, structural versatility, and role in producing pharmaceuticals, agrochemicals, and fine chemicals make it indispensable for both industrial manufacturers and research scientists. As the need for advanced heterocyclic compounds grows, this molecule continues to play a vital role in cutting-edge chemical innovation.
