
N-Benzylglycine Ethyl Ester, identified by the CAS number 6436-90-4, is a valuable organic compound widely used in pharmaceutical research, organic synthesis, and chemical manufacturing. Its unique structure and reactivity make it an essential building block for creating numerous intermediates and active compounds.
This article explores its properties, applications, benefits, and why the compound holds a significant place in modern chemical industries.
N-Benzylglycine Ethyl Ester is an ester derivative of benzylglycine, featuring both amino acid and ester functionalities. This dual nature provides stability and reactivity, making it ideal for multi-step synthesis processes.
Chemical Name: N-Benzylglycine Ethyl Ester
CAS Number: 6436-90-4
Molecular Formula: C11H15NO2
Molecular Weight: Approx. 193.24 g/mol
Appearance: Typically a colorless to pale yellow liquid or oil
Purity: Commonly available in high-purity forms for research and industrial requirements
N-Benzylglycine Ethyl Ester is known for:
Good solubility in organic solvents such as ethanol, methanol, dichloromethane, and acetone
High stability under room temperature conditions
Strong reactivity due to the presence of an ester group and benzyl functional group
These properties make it easy to handle and incorporate into synthetic procedures.
The compound is widely used in the synthesis of:
Active pharmaceutical ingredients (APIs)
Peptide-like molecules
Novel therapeutic compounds
Its ability to participate in nucleophilic substitution and condensation reactions makes it ideal for drug development processes.
N-Benzylglycine Ethyl Ester acts as a flexible intermediate for:
Creating customized amino acid derivatives
Producing chiral compounds
Forming building blocks for advanced chemical structures
Chemical R&D laboratories utilize this compound for:
Reaction mechanism studies
Optimization of synthetic routes
Development of new chemical entities (NCEs)
Manufacturers provide highly refined versions ideal for pharmaceutical-grade processes.
Its ester and amino-acid-like structure allow multiple reaction pathways.
Cost-effective for large-scale processes without compromising quality.
Store in a cool, dry environment
Keep in a well-sealed container to avoid moisture absorption
Use proper PPE: gloves, goggles, lab coat
Handle in a well-ventilated area
N-Benzylglycine Ethyl Ester (CAS 6436-90-4) is a crucial chemical intermediate with broad applications in pharmaceuticals, organic synthesis, and research sectors. Its chemical versatility and stability make it a top choice for industries aiming to develop high-quality, complex compounds efficiently.
Whether you’re involved in drug development or advanced chemical manufacturing, this compound remains a trusted and valuable component in modern synthesis.