6939-23-7 (2-(tert-Butylamino)acetic Acid Hydrochloride): Properties, Uses, and Chemical Importance

Introduction

In pharmaceutical and fine chemical research, amino acid derivatives play a vital role as intermediates and functional building blocks. One such important compound is 6939-23-7 (2-(tert-Butylamino)acetic Acid Hydrochloride). Known for its stability and versatility, this compound is widely used in medicinal chemistry and specialty chemical synthesis. This article explores its properties, applications, and overall chemical importance.


Chemical Identification

The compound consists of an amino-functionalized acetic acid with a tert-butyl substituent, present as a hydrochloride salt. This form enhances solubility and stability, making it suitable for laboratory and industrial use.


Key Physical and Chemical Properties

  • Appearance: White to off-white crystalline powder

  • Solubility: Highly soluble in water and polar solvents

  • Stability: Stable under normal storage conditions

  • pH Behavior: Acidic due to hydrochloride salt formation

These properties make 6939-23-7 easy to handle and reliable for controlled chemical reactions.


Uses and Applications

1. Pharmaceutical Intermediate

2-(tert-Butylamino)acetic acid hydrochloride is commonly used as an intermediate in drug synthesis, especially in compounds involving amino acid frameworks. It supports the development of APIs and biologically active molecules.

2. Medicinal Chemistry Research

The compound is valuable in structure–activity relationship (SAR) studies, helping researchers modify molecular structures to improve drug efficacy and safety.

3. Fine and Specialty Chemicals

Due to its functional amino and carboxylic acid groups, it is used in the synthesis of custom organic molecules, peptides, and advanced chemical derivatives.

4. Academic and R&D Laboratories

Research institutions utilize this compound for experimental synthesis, method development, and chemical innovation projects.


Chemical Importance

The importance of 6939-23-7 (2-(tert-Butylamino)acetic Acid Hydrochloride) lies in its functional versatility. The tert-butylamino group introduces steric control, while the acetic acid backbone allows easy integration into complex molecules. These features make it essential for:

  • Drug discovery and formulation

  • Advanced organic synthesis

  • Chemical process optimization

  • Development of nitrogen-containing compounds

Its hydrochloride form ensures consistency and improved handling across applications.


Handling and Safety Considerations

  • Use appropriate personal protective equipment (PPE)

  • Avoid direct contact with skin and eyes

  • Store in a cool, dry, and well-ventilated area

  • Always consult the Safety Data Sheet (SDS) before use

Following standard laboratory safety practices ensures safe and effective usage.


Conclusion

6939-23-7 (2-(tert-Butylamino)acetic Acid Hydrochloride) is a valuable compound in modern chemistry, particularly in pharmaceutical and fine chemical industries. Its stable properties, broad applicability, and chemical flexibility make it an essential intermediate for research and industrial synthesis. As demand for advanced chemical solutions grows, this compound continues to play a key role in innovation and development.