2-(tert-Butylamino)acetic acid hydrochloride (CAS 6939-23-7) is an important organic intermediate widely recognized for its role in pharmaceutical synthesis, fine chemical manufacturing, and biochemical research. With a unique molecular structure that combines an amino acid backbone with a tert-butyl substituted amine, this compound offers exceptional versatility and reactivity, making it a preferred ingredient for developing high-value specialty compounds.
2-(tert-Butylamino)acetic acid hydrochloride is a hydrochloride salt of a substituted glycine derivative. This modification enhances the compound’s solubility, stability, and handling characteristics, making it suitable for industrial-scale applications.
CAS Number: 6939-23-7
Chemical Name: 2-(tert-Butylamino)acetic acid hydrochloride
Molecular Formula: C6H14ClNO2
Functional Class: Organic intermediate / Amino acid derivative
This compound is valued for its structural features and reactivity profile.
Stable HCl salt, improving shelf life and storage
High solubility in water and polar solvents
Contains both amine and carboxylic groups, enabling diverse transformations
Useful precursor for synthesizing modified amino acids and peptide intermediates
The tert-butyl group provides steric modulation, allowing controlled reactivity during synthesis.
One of the most significant uses of 2-(tert-Butylamino)acetic acid hydrochloride is in the pharmaceutical industry. It serves as:
A precursor for drug candidates
A starting material for API intermediates
A component in the synthesis of bioactive molecules
Its functional groups support peptide coupling, amide bond formation, and structural modifications essential in medicinal chemistry.
In fine chemical manufacturing, this compound is utilized for:
Producing novel amino acid derivatives
Synthesis of specialty reagents
Creating molecular scaffolds for research compounds
The protective nature of the tert-butyl group allows selective transformations without unwanted side reactions.
Researchers use this compound in:
Structure–activity relationship (SAR) studies
Development of enzyme substrates and inhibitors
Preparation of complex organic molecules
Its dual functional groups make it a valuable tool for investigating chemical pathways and designing molecular prototypes.
The rising demand for custom pharmaceuticals and specialty organic intermediates has made CAS 6939-23-7 increasingly valuable in the global chemical market.
High versatility in synthetic pathways
Consistency in industrial-scale production
Compatibility with modern organic synthesis techniques
Cost-effective building block for high-value compounds
Manufacturers and R&D organizations rely on this compound because it simplifies multi-step reactions and enhances process efficiency.
Although stable, the compound should be handled with standard laboratory precautions:
Avoid contact with moisture
Use PPE (gloves, eye protection, lab coat)
Store in a cool, dry place
Follow supplier MSDS guidelines for detailed safety procedures
2-(tert-Butylamino)acetic acid hydrochloride (CAS 6939-23-7) plays a pivotal role in pharmaceutical development, fine chemical synthesis, and advanced research. Its unique structural features—combining a substituted amine with an amino acid framework—make it an indispensable intermediate in modern chemical industries. As the market for complex organic molecules continues to expand, this compound remains central to innovation and high-performance synthesis.
