Overview & Chemical Identity
CAS Number: 95306-64-2
Chemical Name: 4-Amino-5-methylpyridin-2-ol
IUPAC Name: 4-Amino-5-methylpyridin-2-ol
Synonyms:
4-Amino-5-methyl-2-hydroxypyridine;
5-Methyl-4-aminopyridin-2-ol;
4-Amino-5-methyl-2-pyridinol
Molecular Formula: C₆H₈N₂O
Molecular Weight: ~124.14 g/mol
Physical & Chemical Properties
Appearance: Off-white to light beige crystalline powder
Physical State: Solid
Melting Point: Typically reported in the range of 160–170 °C (may vary depending on purity)
Boiling Point: Not well defined; may decompose at elevated temperatures
Solubility:
Soluble in polar organic solvents such as methanol, ethanol, and DMSO; moderately soluble in water
Stability:
Stable under standard laboratory conditions; may be sensitive to prolonged exposure to air and moisture
Structural & Molecular Identifiers
Functional Groups:
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Amino group (–NH₂)
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Hydroxyl group (–OH)
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Heterocyclic aromatic pyridine ring
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Methyl substituent (–CH₃)
Chemical Class:
Aminopyridine derivative / Heterocyclic aromatic compound
SMILES (representative):
CC1=C(N)C(=NC=C1)O
InChI Key (representative):
(Varies by database; available from chemical registries)
Functionality & Applications
Pharmaceutical Intermediate
95306-64-2 is widely used as a building block in pharmaceutical synthesis, particularly for:
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Preparation of heterocyclic drug intermediates
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Development of vitamin-related derivatives
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Synthesis of biologically active nitrogen-containing compounds
Its aminopyridine structure makes it valuable in medicinal chemistry research.
Fine Chemical & Specialty Synthesis
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Intermediate for agrochemical compounds
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Precursor in dye and pigment chemistry
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Building block for advanced heterocyclic frameworks
The presence of amino and hydroxyl functional groups enables diverse chemical modifications and multi-step reactions.
Research & Development
Commonly employed in:
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Organic synthesis research
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Medicinal chemistry programs
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Structure–activity relationship (SAR) studies
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Development of new heterocyclic scaffolds
Its dual functional groups (–NH₂ and –OH) provide flexibility in substitution and derivatization reactions.
Safety & Handling
GHS Classification (typical for similar compounds):
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May cause skin and eye irritation
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May cause respiratory irritation
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Harmful if swallowed
Common Hazard Statements:
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H302: Harmful if swallowed
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H315: Causes skin irritation
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H319: Causes serious eye irritation
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H335: May cause respiratory irritation
Precautionary Statements:
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P261: Avoid breathing dust
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P280: Wear protective gloves and eye protection
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P305 + P351 + P338: IF IN EYES, rinse cautiously with water and remove contact lenses
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P301 + P312: IF SWALLOWED, call a doctor if you feel unwell
Handle in a well-ventilated laboratory environment using appropriate personal protective equipment (PPE).
Practical Details & Supplier Information
Typical Purity: 97–99% (Research and Industrial Grade)
Storage Conditions:
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Store in a tightly sealed container
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Keep in a cool, dry, and well-ventilated area
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Protect from moisture and direct sunlight
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Keep away from strong oxidizing agents
Commercial Use:
Available from specialty chemical suppliers for research, pharmaceutical intermediate development, and industrial organic synthesis.
Not intended for direct pharmaceutical, food, or diagnostic use without proper regulatory compliance.
Summary Statement
95306-64-2 (4-Amino-5-methylpyridin-2-ol) is an important heterocyclic aminopyridine derivative widely used as a pharmaceutical and fine chemical intermediate. Its combination of amino and hydroxyl functional groups within a pyridine framework makes it a versatile building block for medicinal chemistry, agrochemical synthesis, and advanced organic research applications.
As a trusted manufacturer and supplier in Hyderabad, SriniChem provides high-quality 95306-64-2 (4-Amino-5-methylpyridin-2-ol) produced under strict quality control standards. Our product, with CAS No: 95306-64-2, is suitable for both research and industrial use. Choose SriniChem for reliable supply, technical expertise, and customer-focused service. Contact SriniChem today for 4-Amino-5-methylpyridin-2-ol
