N-Benzylglycine Ethyl Ester (CAS No. 6436-90-4) is an important organic compound widely used as an intermediate in pharmaceutical research and fine chemical synthesis. With its well-defined structure and functional versatility, this compound plays a valuable role in the development of complex molecules for research and industrial applications.
Chemical Name: N-Benzylglycine Ethyl Ester
CAS Number: 6436-90-4
Molecular Formula: C₁₁H₁₅NO₂
Molecular Weight: ~193.24 g/mol
Chemical Class: Amino acid ester derivative
This compound features a benzyl-protected amino group and an ethyl ester functionality, making it a useful building block in organic synthesis.
N-Benzylglycine Ethyl Ester exhibits properties that make it suitable for laboratory and industrial use:
Typically appears as a colorless to pale yellow liquid or solid
Soluble in common organic solvents such as ethanol, methanol, and dichloromethane
Low solubility in water
Stable under standard storage conditions
These properties enable ease of handling and compatibility with various synthetic processes.
This compound is commonly used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The benzyl group serves as a protecting group that can be selectively removed during later stages of synthesis.
N-Benzylglycine Ethyl Ester is valuable in peptide chemistry and amino acid modification reactions. Its ester group allows further functionalization, supporting the creation of more complex molecular structures.
In academic and industrial research laboratories, this compound is used in studies related to medicinal chemistry, structure–activity relationships (SAR), and chemical reaction mechanisms.
The compound contributes to the production of specialty chemicals used in advanced research, analytical standards, and customized synthesis projects.
To ensure safe and effective use, standard chemical handling practices should be followed:
Store in a tightly sealed container in a cool, dry place
Protect from moisture and excessive heat
Use appropriate personal protective equipment (PPE)
Refer to the Safety Data Sheet (SDS) for detailed handling instructions
The importance of 6436-90-4 (N-Benzylglycine Ethyl Ester) lies in its structural flexibility. The presence of both an ester group and a benzyl-protected amine allows chemists to carry out selective reactions, making it a valuable intermediate in multi-step synthesis pathways.
N-Benzylglycine Ethyl Ester is a versatile and reliable compound with broad applications in pharmaceutical development, organic synthesis, and research laboratories. Its stability, reactivity, and functional design make it an essential building block in modern chemistry.
